iPTMnet Report for O43147 (SGSM2)
Protein Information
UniProt AC / UniProt ID | O43147 / SGSM2_HUMAN |
Protein Name | Small G protein signaling modulator 2 |
Gene Name | Name: SGSM2 Synonyms:KIAA0397,RUTBC1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O43147 |
PRO Name | small G protein signaling modulator 2 (human) |
Definition | A small G protein signaling modulator 2 that is encoded in the genome of human. |
Short Label | hSGSM2 |
Category | organism-gene |
O43147 (SGSM2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K100 | Ubiquitination | score1 | PhosphoSitePlus | |||
S102 | Phosphorylation | score1 | PhosphoSitePlus | |||
S105 | Phosphorylation | score1 | PhosphoSitePlus | |||
S123 | Phosphorylation | score1 | PhosphoSitePlus | |||
K187 | Ubiquitination | score1 | PhosphoSitePlus | |||
S216 | Phosphorylation | score1 | PhosphoSitePlus | |||
S231 | Phosphorylation | score1 | PhosphoSitePlus | |||
S399 | Phosphorylation | score1 | PhosphoSitePlus | |||
S402 | Phosphorylation | score1 | PhosphoSitePlus | |||
R412 | Methylation | score1 | PhosphoSitePlus | |||
R419 | Methylation | score1 | PhosphoSitePlus | |||
K492 | Ubiquitination | score1 | PhosphoSitePlus | |||
K545 | Ubiquitination | score1 | PhosphoSitePlus | |||
K554 | Ubiquitination | score1 | PhosphoSitePlus | |||
K590 | Acetylation | score1 | PhosphoSitePlus | |||
K611 | Acetylation | score1 | PhosphoSitePlus | |||
K631 | Ubiquitination | score1 | PhosphoSitePlus | |||
S636 | Phosphorylation | score1 | PhosphoSitePlus | |||
S637 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S444 | Phosphorylation | score1 | PhosphoSitePlus | |||
S460 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S105 | N105 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
S402 | F402 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
R412 | W412 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ] | |
K545 | E545 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
S637 | T637 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] |