iPTMnet Report for O15492 (RGS16)
Protein Information
UniProt AC / UniProt ID | O15492 / RGS16_HUMAN |
Protein Name | Regulator of G-protein signaling 16 |
Gene Name | Name: RGS16 Synonyms:RGSR; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O15492 |
PRO Name | regulator of G-protein signaling 16 (human) |
Definition | A regulator of G-protein signaling 16 that is encoded in the genome of human. |
Short Label | hRGS16 |
Category | organism-gene |
O15492 (RGS16) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
C12 | Methylation | score1 | IEDB | 31844290 | ||
K41 | Ubiquitination | score1 | PhosphoSitePlus | |||
S71 | Phosphorylation | score1 | PhosphoSitePlus | |||
S72 | Phosphorylation | score1 | PhosphoSitePlus | |||
K73 | Acetylation | score1 | PhosphoSitePlus | |||
C98 | Methylation | score1 | IEDB | 31844290 | ||
Y168 | Phosphorylation | P41240 (CSK) , P07948 (LYN) , P12931 (SRC) , P00533 (EGFR) | score4 | HPRD neXtProt phospho.ELM PhosphoSitePlus RLIMS-P Signor UniProt | 12588871, 11602604 | |
K173 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y177 | Phosphorylation | P07948 (LYN) , P12931 (SRC) , P00533 (EGFR) | score4 | HPRD phospho.ELM PhosphoSitePlus RLIMS-P Signor UniProt | 12588871, 11602604 | |
S195 | Phosphorylation | score1 | HPRD | 11522288 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K41 | R41 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
S71 | I71 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
S195 | N195 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S195 | C195 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] |