iPTMnet Report for O15427 (SLC16A3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15427 / MOT4_HUMAN
Protein Name Monocarboxylate transporter 4
Gene Name Name: SLC16A3
Synonyms:MCT3;
Organism Homo sapiens (Human)

PRO ID PR:O15427
DAG View
PRO Name monocarboxylate transporter 4 (human)
Definition A monocarboxylate transporter 4 that is encoded in the genome of human.
Short Label hSLC16A3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15427 (SLC16A3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S35 Phosphorylation PhosphoSitePlus
Y36 Phosphorylation PhosphoSitePlus
C108 Methylation IEDB 31844290
C161 Methylation IEDB 31844290
K254 Sumoylation PhosphoSitePlus
K262 Sumoylation PhosphoSitePlus
C409 Methylation IEDB 31844290
K415 Ubiquitination PhosphoSitePlus
K428 Ubiquitination PhosphoSitePlus
K431 Ubiquitination PhosphoSitePlus
S436 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18578522, 23186163, 17081983, ...19651622, 20068231
K448 Sumoylation PhosphoSitePlus
K448 Ubiquitination PhosphoSitePlus
K453 Ubiquitination PhosphoSitePlus
T460 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 16964243, 18767875, ...18669648, 20068231, 17081983
T463 Phosphorylation HPRD   PhosphoSitePlus 20068231
S464 O-Glycosylation GlyGen 30444036, 35083852, 35254053
S464 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 18578522, 17081983, ...19651622, 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K262 N262 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K431 Q431 Biomuta DOID:363 / uterine cancer [ icgc ]
K431 T431 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T463 A463 Biomuta DOID:263 / kidney cancer [ cosmic ]
S464 G464 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]