iPTMnet Report for O15400 (STX7)
Protein Information
| UniProt AC / UniProt ID | O15400 / STX7_HUMAN |
| Protein Name | Syntaxin-7 |
| Gene Name | Name: STX7 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O15400 |
| PRO Name | syntaxin-7 (human) |
| Definition | A syntaxin-7 that is encoded in the genome of human. |
| Short Label | hSTX7 |
| Category | organism-gene |
O15400 (STX7) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S2 | Acetylation | score1 | UniProt | 19413330, 22814378, 12665801, ... | ||
| S2 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y3 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T4 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K24 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C28 | S-Nitrosylation | score0 | dbSNO | 19483679 | ||
| T41 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S45 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K55 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K71 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S75 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| T78 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| T79 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S81 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K87 | Acetylation | score1 | PhosphoSitePlus | |||
| K90 | Acetylation | score1 | PhosphoSitePlus | |||
| K106 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S125 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S126 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P UniProt | 31665227, 23186163 | ||
| S129 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648, 23186163, 21406692 | ||
| S131 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S136 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K138 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S144 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T149 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T161 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S173 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S205 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S2 | Phosphorylation | score0 | HPRD | 18578522 | ||
| Y3 | Phosphorylation | score0 | HPRD | 19413330 | ||
| T79 | Phosphorylation | score0 | HPRD | 15345747, 18578522, 19664994, ... | ||
| S126 | Phosphorylation | score0 | HPRD | 18578522 | ||
| S129 | Phosphorylation | score0 | HPRD | 19651622, 20166139, 18669648 | ||
| S131 | Phosphorylation | score0 | HPRD | 20166139 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S81 | N81 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S125 | C125 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S173 | C173 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| S205 | C205 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
| S205 | G205 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
DAG View