iPTMnet Report for O15397 (IPO8)
Protein Information
UniProt AC / UniProt ID | O15397 / IPO8_HUMAN |
Protein Name | Importin-8 |
Gene Name | Name: IPO8 Synonyms:RANBP8; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O15397 |
PRO Name | importin-8 (human) |
Definition | An importin-8 that is encoded in the genome of human. |
Short Label | hIPO8 |
Category | organism-gene |
O15397 (IPO8) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K11 | Ubiquitination | score1 | PhosphoSitePlus | |||
T13 | Phosphorylation | score1 | PhosphoSitePlus | |||
K17 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y30 | Phosphorylation | score1 | PhosphoSitePlus | |||
K31 | Ubiquitination | score1 | PhosphoSitePlus | |||
K202 | Ubiquitination | score1 | PhosphoSitePlus | |||
K284 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y374 | Phosphorylation | score1 | PhosphoSitePlus | |||
K380 | Ubiquitination | score1 | PhosphoSitePlus | |||
S389 | Phosphorylation | score1 | PhosphoSitePlus | |||
K403 | Ubiquitination | score1 | PhosphoSitePlus | |||
K503 | Ubiquitination | score1 | PhosphoSitePlus | |||
K510 | Ubiquitination | score1 | PhosphoSitePlus | |||
S524 | Phosphorylation | score1 | PhosphoSitePlus | |||
S527 | Phosphorylation | score1 | PhosphoSitePlus | |||
K565 | Acetylation | score1 | PhosphoSitePlus | |||
S595 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y598 | Phosphorylation | score1 | PhosphoSitePlus | |||
C736 | Methylation | score1 | IEDB | 31844290 | ||
S842 | Phosphorylation | score1 | IEDB | 30784271 | ||
S902 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 21406692, 19690332 | ||
S903 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 21406692, 19690332 | ||
T908 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1003 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1010 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K403 | N403 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ] | |
K503 | R503 | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
K503 | N503 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S595 | C595 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
Y598 | H598 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
S902 | A902 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
T1003 | M1003 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] | |
T1003 | S1003 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |