iPTMnet Report for O15392 (BIRC5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15392 / BIRC5_HUMAN
Protein Name Baculoviral IAP repeat-containing protein 5
Gene Name Name: BIRC5
Synonyms:API4,IAP4;
Organism Homo sapiens (Human)

PRO ID PR:O15392
DAG View
PRO Name baculoviral IAP repeat-containing protein 5 (human)
Definition A baculoviral IAP repeat-containing protein 5 that is encoded in the genome of human.
Short Label hBIRC5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15392 (BIRC5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K15 Ubiquitination PhosphoSitePlus
S20 Phosphorylation P53350 (PLK1) , P17612 (PRKACA) PhosphoSitePlus   Signor   UniProt 21148584, 27332895, 17612487, ...20427271
T21 Phosphorylation P53350 (PLK1) PhosphoSitePlus 21148584, 20427271
K23 Acetylation PhosphoSitePlus   UniProt 20826784
K23 Ubiquitination PhosphoSitePlus
T34 Phosphorylation P06493 (CDK1) , Q96GD4 (AURKB) HPRD   phospho.ELM   PhosphoSitePlus   Signor   UniProt 18691976, 11069302, 12517802, ...16565220, 11861764, 24866247, 24478433, 20068231
C46 Methylation IEDB 31844290
T48 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   UniProt 21252625
K78 Ubiquitination PhosphoSitePlus
K90 Acetylation PhosphoSitePlus   UniProt 20826784
K90 Ubiquitination PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
K110 Acetylation PhosphoSitePlus   UniProt 20826784
K112 Acetylation PhosphoSitePlus   UniProt 20826784
K115 Acetylation PhosphoSitePlus   UniProt 20826784
T117 Phosphorylation Q96GD4 (AURKB) neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 14610074, 17457057
K120 Acetylation PhosphoSitePlus
K121 Acetylation PhosphoSitePlus   UniProt 20826784
K122 Acetylation PhosphoSitePlus
K129 Acetylation PhosphoSitePlus   UniProt 20826784
K130 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T34 Phosphorylation PRO 11069302
T117 Phosphorylation PRO 14610074
Site PTM Type PTM Enzyme Score Source PMID
T34 Phosphorylation P06493 (CDK1) HPRD 18691976, 11069302, 11861764, ...20068231, 16565220


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000026283 (hBIRC5/iso:1/Phos:1) pT34 PRO 11069302
PR:000026285 (hBIRC5/iso:1/Phos:2) pT117 PRO 14610074


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:000035525 (hH3(any)/InitMet-/Phos:1) increased Interaction PR:O15392 (hBIRC5) PRO 21658950
PR:Q53HL2 (hCDCA8) Interaction PR:O15392 (hBIRC5) PRO
PR:Q96GD4 (hAURKB) Interaction PR:O15392 (hBIRC5) PRO
PR:Q9NQS7 (hINCENP) Interaction PR:O15392 (hBIRC5) PRO
PR:Q9NR28-1 (hDIABLO/iso:1) Interaction PR:O15392 (hBIRC5) PRO 12660240