iPTMnet Report for O15305 (PMM2)
Protein Information
UniProt AC / UniProt ID | O15305 / PMM2_HUMAN |
Protein Name | Phosphomannomutase 2 |
Gene Name | Name: PMM2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:O15305 |
PRO Name | phosphomannomutase 2 (human) |
Definition | A phosphomannomutase 2 that is encoded in the genome of human. |
Short Label | hPMM2 |
Category | organism-gene |
O15305 (PMM2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 22814378, 22223895 | ||
K26 | Ubiquitination | score1 | PhosphoSitePlus | |||
K34 | Ubiquitination | score1 | PhosphoSitePlus | |||
S47 | Phosphorylation | score1 | PhosphoSitePlus | |||
K51 | Ubiquitination | score1 | PhosphoSitePlus | |||
K63 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y76 | Phosphorylation | score1 | PhosphoSitePlus | |||
K77 | Ubiquitination | score1 | PhosphoSitePlus | |||
S130 | Phosphorylation | score1 | PhosphoSitePlus | |||
S137 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y145 | Phosphorylation | score1 | PhosphoSitePlus | |||
K149 | Acetylation | score1 | PhosphoSitePlus | |||
K156 | Ubiquitination | score1 | PhosphoSitePlus | |||
K202 | Acetylation | score1 | PhosphoSitePlus | |||
K202 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S47 | L47 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K51 | E51 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
K77 | E77 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S137 | N137 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |