iPTMnet Report for O15287 (FANCG)
Protein Information
UniProt AC / UniProt ID | O15287 / FANCG_HUMAN |
Protein Name | Fanconi anemia group G protein |
Gene Name | Name: FANCG Synonyms:XRCC9; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O15287 |
PRO Name | Fanconi anemia group G protein (human) |
Definition | A Fanconi anemia group G protein that is encoded in the genome of human. |
Short Label | hFANCG |
Category | organism-gene |
O15287 (FANCG) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S7 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus RLIMS-P UniProt | 15367677, 20450923, 15299017, ... | ||
K28 | Ubiquitination | score1 | PhosphoSitePlus | |||
C75 | Methylation | score1 | IEDB | 31844290 | ||
K182 | Ubiquitination | score1 | PhosphoSitePlus | |||
K258 | Ubiquitination | score1 | PhosphoSitePlus | |||
K347 | Ubiquitination | score1 | PhosphoSitePlus | |||
S383 | Phosphorylation | P06493 (CDK1) | score4 | HPRD neXtProt PhosphoSitePlus RLIMS-P | 15367677, 9242535 | |
S387 | Phosphorylation | P06493 (CDK1) | score4 | HPRD neXtProt phospho.ELM PhosphoSitePlus RLIMS-P Signor | 15367677, 9242535 | |
K430 | Ubiquitination | score1 | PhosphoSitePlus | |||
T487 | Phosphorylation | P06493 (CDK1) | score2 | neXtProt | 9242535 | |
K491 | Ubiquitination | score1 | PhosphoSitePlus | |||
K504 | Ubiquitination | score1 | PhosphoSitePlus | |||
T557 | Phosphorylation | score1 | PhosphoSitePlus | |||
K559 | Ubiquitination | score1 | PhosphoSitePlus | |||
K618 | Ubiquitination | score1 | PhosphoSitePlus |
Proteoforms
PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
---|---|---|---|---|---|
PR:000025731 (hFANCG/iso:1/Phos:1) | pS7,pS383,pS387 | PRO | 15367677, 18212739 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S7 | F7 | Biomuta | DOID:1324 / lung cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ] | |
S7 | A7 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
S7 | T7 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S383 | F383 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] | |
T487 | A487 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K504 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K618 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |