iPTMnet Report for O15145 (ARPC3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15145 / ARPC3_HUMAN
Protein Name Actin-related protein 2/3 complex subunit 3
Gene Name Name: ARPC3
Synonyms:ARC21;
Organism Homo sapiens (Human)

PRO ID PR:O15145
DAG View
PRO Name actin-related protein 2/3 complex subunit 3 (human)
Definition An actin-related protein 2/3 complex subunit 3 that is encoded in the genome of human.
Short Label hARPC3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15145 (ARPC3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y4 Phosphorylation PhosphoSitePlus
T13 Phosphorylation PhosphoSitePlus
K14 Ubiquitination PhosphoSitePlus
K29 Methylation PhosphoSitePlus
K29 Ubiquitination PhosphoSitePlus
K37 Acetylation PhosphoSitePlus
K37 Ubiquitination PhosphoSitePlus
Y47 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18083107, 19690332
Y48 Phosphorylation PhosphoSitePlus
K50 Acetylation PhosphoSitePlus
K56 Acetylation PhosphoSitePlus   UniProt 19608861
K56 Ubiquitination PhosphoSitePlus
K61 Acetylation PhosphoSitePlus   UniProt 19608861
C78 Methylation IEDB 31844290
K81 Ubiquitination PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
C145 Methylation IEDB 31844290
K147 Acetylation PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
K155 Acetylation PhosphoSitePlus
K155 Ubiquitination PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
C162 Methylation IEDB 31844290
K165 Acetylation PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
K171 Acetylation PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K61 N61 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K147 N147 Biomuta DOID:9256 / colorectal cancer [ icgc ]