iPTMnet Report for O15144 (ARPC2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15144 / ARPC2_HUMAN
Protein Name Actin-related protein 2/3 complex subunit 2
Gene Name Name: ARPC2
Synonyms:ARC34;ORFNames:PRO2446;
Organism Homo sapiens (Human)

PRO ID PR:O15144
DAG View
PRO Name actin-related protein 2/3 complex subunit 2 (human)
Definition An actin-related protein 2/3 complex subunit 2 that is encoded in the genome of human.
Short Label hARPC2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15144 (ARPC2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K27 Ubiquitination PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
K77 Ubiquitination PhosphoSitePlus
S108 Phosphorylation PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
S123 Phosphorylation PhosphoSitePlus
K127 Acetylation PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
T151 Phosphorylation PhosphoSitePlus
Y153 Phosphorylation PhosphoSitePlus
S156 Phosphorylation PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
K186 Acetylation PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
T194 Phosphorylation PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus
T240 Phosphorylation HPRD 20068231
Y250 Phosphorylation PhosphoSitePlus
Y253 Phosphorylation PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
Y261 Phosphorylation PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
K275 Acetylation PhosphoSitePlus   UniProt 19608861
K275 Ubiquitination PhosphoSitePlus
K286 Acetylation PhosphoSitePlus
K290 Ubiquitination PhosphoSitePlus
K295 Acetylation PhosphoSitePlus   UniProt 19608861
K295 Methylation PhosphoSitePlus
K295 Ubiquitination PhosphoSitePlus
T296 Phosphorylation PhosphoSitePlus
S299 Phosphorylation IEDB 27920218


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K127 E127 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S156 F156 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K179 N179 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T194 I194 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y250 C250 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K275 N275 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K286 R286 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S299 Y299 Biomuta DOID:1324 / lung cancer [ cosmic ]