iPTMnet Report for O15117 (FYB1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15117 / FYB1_HUMAN
Protein Name FYN-binding protein 1
Gene Name Name: FYB1
Synonyms:FYB,SLAP130;
Organism Homo sapiens (Human)

PRO ID PR:O15117
DAG View
PRO Name FYN-binding protein 1 (human)
Definition A FYN-binding protein 1 that is encoded in the genome of human.
Short Label hFYB1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15117 (FYB1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K3 Acetylation PhosphoSitePlus   UniProt 19608861
Y4 Phosphorylation PhosphoSitePlus
S30 Phosphorylation PhosphoSitePlus
S46 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18088087, 19690332
T94 Phosphorylation PhosphoSitePlus
K111 Acetylation PhosphoSitePlus
K111 Ubiquitination PhosphoSitePlus
K149 Acetylation PhosphoSitePlus
T158 Phosphorylation phospho.ELM   PhosphoSitePlus 18088087
T161 O-Glycosylation GlyGen 35132862, 29351928
T161 Phosphorylation PhosphoSitePlus
S162 O-Glycosylation GlyGen 35132862, 29351928
K167 Ubiquitination PhosphoSitePlus
K179 Acetylation PhosphoSitePlus
S184 Phosphorylation PhosphoSitePlus
S209 Phosphorylation PhosphoSitePlus
S214 Phosphorylation PhosphoSitePlus
S222 Phosphorylation PhosphoSitePlus
K223 Ubiquitination PhosphoSitePlus
S225 Phosphorylation PhosphoSitePlus   UniProt 23186163
S233 Phosphorylation PhosphoSitePlus
S235 Phosphorylation PhosphoSitePlus
S245 Phosphorylation PhosphoSitePlus
K265 Acetylation PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
K292 Ubiquitination PhosphoSitePlus
K298 Ubiquitination PhosphoSitePlus
S306 Phosphorylation PhosphoSitePlus
T308 Phosphorylation PhosphoSitePlus
S318 Phosphorylation PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
S329 Phosphorylation PhosphoSitePlus   UniProt 23186163
K334 Acetylation PhosphoSitePlus
K373 Ubiquitination PhosphoSitePlus
T374 O-Glycosylation GlyGen 35132862, 29351928
T374 Phosphorylation PhosphoSitePlus
T385 Phosphorylation PhosphoSitePlus
S386 Phosphorylation PhosphoSitePlus
Y387 Phosphorylation PhosphoSitePlus
K425 Acetylation PhosphoSitePlus
S432 Phosphorylation PhosphoSitePlus
S457 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
T461 Phosphorylation PhosphoSitePlus
Y462 Phosphorylation PhosphoSitePlus
K496 Ubiquitination PhosphoSitePlus
K503 Ubiquitination PhosphoSitePlus
T507 Phosphorylation PhosphoSitePlus
K549 Ubiquitination PhosphoSitePlus
S558 Phosphorylation PhosphoSitePlus
Y559 Phosphorylation P06241 (FYN) IntAct   PhosphoSitePlus 10671560, 20661443
Y561 Phosphorylation PhosphoSitePlus
Y571 Phosphorylation P06241 (FYN) phospho.ELM   PhosphoSitePlus   UniProt 18088087, 18083107, 20661443, ...26246585, 19690332, 16497976
S573 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18088087, 19690332
K575 Ubiquitination PhosphoSitePlus
Y595 Phosphorylation P06241 (FYN) IntAct   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 22074159, 20661443, 26246585, ...10570256, 10409671
Y625 Phosphorylation P06241 (FYN) IntAct   PhosphoSitePlus 26246585, 10409671
Y651 Phosphorylation P06241 (FYN) IntAct   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 10570256, 20661443, 26246585, ...10409671, 19690332
Y701 Phosphorylation PhosphoSitePlus
Y709 Phosphorylation PhosphoSitePlus
T711 Phosphorylation PhosphoSitePlus
K730 Ubiquitination PhosphoSitePlus
S734 Phosphorylation PhosphoSitePlus
K745 Ubiquitination PhosphoSitePlus
K754 Ubiquitination PhosphoSitePlus
Y755 Phosphorylation P06241 (FYN) PhosphoSitePlus 20661443
Y757 Phosphorylation P06241 (FYN) PhosphoSitePlus 20661443
Y762 Phosphorylation PhosphoSitePlus
Y771 Phosphorylation P06241 (FYN) PhosphoSitePlus 26246585, 20661443
Y780 Phosphorylation P06241 (FYN) PhosphoSitePlus 26246585, 20661443
Site PTM Type PTM Enzyme Score Source PMID
S46 Phosphorylation HPRD 18088087, 20058876
T158 Phosphorylation HPRD 18088087
T161 Phosphorylation HPRD 18491316
Y571 Phosphorylation HPRD 18088087, 15144186, 16497976
S573 Phosphorylation HPRD 18088087, 20058876, 15144186
Y595 Phosphorylation P06241 (FYN) HPRD 10570256
Y651 Phosphorylation P06241 (FYN) HPRD 10570256
T711 Phosphorylation HPRD 19413330
Y755 Phosphorylation HPRD 15144186
Y757 Phosphorylation HPRD 15144186
Site PTM Type PTM Enzyme Score Source PMID
S46 Phosphorylation HPRD 18088087, 20058876
T158 Phosphorylation HPRD 18088087
T161 Phosphorylation HPRD 18491316
Y571 Phosphorylation HPRD 18088087, 15144186, 16497976
S573 Phosphorylation HPRD 18088087, 20058876, 15144186
Y595 Phosphorylation P06241 (FYN) HPRD 10570256
S645 Phosphorylation PhosphoSitePlus
T647 Phosphorylation PhosphoSitePlus
S665 Phosphorylation PhosphoSitePlus
S673 Phosphorylation PhosphoSitePlus
Y697 Phosphorylation P06241 (FYN) HPRD 10570256
T757 Phosphorylation HPRD 19413330
Y801 Phosphorylation HPRD 15144186
Y803 Phosphorylation HPRD 15144186


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation O15117 (FYB1) Y651 Q13094 (LCP2) unknown eFIP 10570256