iPTMnet Report for O15033 (AREL1)
Protein Information
UniProt AC / UniProt ID | O15033 / AREL1_HUMAN |
Protein Name | Apoptosis-resistant E3 ubiquitin protein ligase 1 |
Gene Name | Name: AREL1 Synonyms:KIAA0317; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O15033 |
PRO Name | apoptosis-resistant E3 ubiquitin protein ligase 1 (human) |
Definition | An apoptosis-resistant E3 ubiquitin protein ligase 1 that is encoded in the genome of human. |
Short Label | hAREL1 |
Category | organism-gene |
O15033 (AREL1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y47 | Phosphorylation | score1 | PhosphoSitePlus | |||
S59 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y84 | Phosphorylation | score1 | PhosphoSitePlus | |||
S327 | Phosphorylation | score1 | PhosphoSitePlus | |||
T328 | Phosphorylation | score1 | PhosphoSitePlus | |||
S337 | Phosphorylation | score1 | PhosphoSitePlus | |||
T343 | Phosphorylation | score1 | PhosphoSitePlus | |||
K352 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y354 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y356 | Phosphorylation | score1 | PhosphoSitePlus | |||
S358 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y368 | Phosphorylation | score1 | PhosphoSitePlus | |||
K431 | Ubiquitination | score1 | PhosphoSitePlus | |||
S436 | Phosphorylation | score1 | PhosphoSitePlus | |||
K442 | Ubiquitination | score1 | PhosphoSitePlus | |||
K477 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y564 | Phosphorylation | score1 | PhosphoSitePlus | |||
S566 | Phosphorylation | score1 | PhosphoSitePlus | |||
S567 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y572 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T783 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S59 | Y59 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
Y84 | C84 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
S327 | Y327 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] | |
S337 | L337 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
T343 | P343 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
K352 | Q352 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
Y354 | H354 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
S436 | Y436 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S567 | F567 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S567 | Y567 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |