iPTMnet Report for O15014 (ZNF609)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15014 / ZN609_HUMAN
Protein Name Zinc finger protein 609
Gene Name Name: ZNF609
Synonyms:KIAA0295;
Organism Homo sapiens (Human)

PRO ID PR:O15014
DAG View
PRO Name zinc finger protein 609 (human)
Definition A zinc finger protein 609 that is encoded in the genome of human.
Short Label hZNF609
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15014 (ZNF609) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S8 Phosphorylation PhosphoSitePlus
S23 Phosphorylation PhosphoSitePlus
S52 Phosphorylation PhosphoSitePlus
T76 Phosphorylation PhosphoSitePlus
S95 Phosphorylation PhosphoSitePlus
K97 Acetylation PhosphoSitePlus
S100 Phosphorylation PhosphoSitePlus
K101 Acetylation PhosphoSitePlus
T106 Phosphorylation PhosphoSitePlus
S107 Phosphorylation PhosphoSitePlus
S112 Phosphorylation PhosphoSitePlus
K118 Acetylation PhosphoSitePlus
S125 Phosphorylation PhosphoSitePlus
K157 Acetylation PhosphoSitePlus
S163 Phosphorylation PhosphoSitePlus
S164 Phosphorylation PhosphoSitePlus
S165 Phosphorylation PhosphoSitePlus
S167 Phosphorylation PhosphoSitePlus
S252 Phosphorylation PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus
Y338 Phosphorylation PhosphoSitePlus
S358 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T360 Phosphorylation PhosphoSitePlus
S361 Phosphorylation PhosphoSitePlus
S379 Phosphorylation PhosphoSitePlus   UniProt 23186163
T381 Phosphorylation PhosphoSitePlus   UniProt 23186163
S413 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S417 Phosphorylation PhosphoSitePlus
S433 Phosphorylation PhosphoSitePlus   UniProt 23186163
S446 Phosphorylation PhosphoSitePlus   UniProt 23186163
S452 Phosphorylation PhosphoSitePlus   UniProt 23186163
S453 Phosphorylation PhosphoSitePlus
S454 Phosphorylation PhosphoSitePlus
S457 Phosphorylation PhosphoSitePlus
T465 Phosphorylation PhosphoSitePlus
S467 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 18669648, 23186163
S470 Phosphorylation PhosphoSitePlus   UniProt 23186163
T472 Phosphorylation PhosphoSitePlus
T478 Phosphorylation PhosphoSitePlus
S491 Phosphorylation PhosphoSitePlus
S533 Phosphorylation PhosphoSitePlus
S560 Phosphorylation PhosphoSitePlus
S564 Phosphorylation PhosphoSitePlus
T566 Phosphorylation PhosphoSitePlus
K568 Acetylation PhosphoSitePlus
S576 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...15302935, 18669648, 20068231
S578 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...15302935, 18669648, 20068231
S580 Phosphorylation PhosphoSitePlus
S581 Phosphorylation PhosphoSitePlus
S605 Phosphorylation PhosphoSitePlus
S609 Phosphorylation PhosphoSitePlus
T619 Phosphorylation PhosphoSitePlus
S620 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
T722 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
S737 Phosphorylation PhosphoSitePlus
S738 Phosphorylation PhosphoSitePlus
S743 Phosphorylation PhosphoSitePlus   UniProt 23186163
T746 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
S758 Phosphorylation PhosphoSitePlus   UniProt 23186163
S763 Phosphorylation PhosphoSitePlus
S764 Phosphorylation PhosphoSitePlus
S778 Phosphorylation PhosphoSitePlus
K789 Sumoylation PhosphoSitePlus
Y796 Phosphorylation PhosphoSitePlus
S797 Phosphorylation PhosphoSitePlus
T799 Phosphorylation PhosphoSitePlus
S804 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S806 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T816 Phosphorylation PhosphoSitePlus
T817 Phosphorylation PhosphoSitePlus
T819 Phosphorylation PhosphoSitePlus
T823 Phosphorylation PhosphoSitePlus   UniProt 23186163
T829 Phosphorylation PhosphoSitePlus
T840 Phosphorylation IEDB   phospho.ELM   PhosphoSitePlus 18669648, 32157095
S842 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18669648, 15302935, ...19690332
Y845 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S846 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S849 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 15302935, ...18669648, 19690332
S886 Phosphorylation PhosphoSitePlus
S900 Phosphorylation PhosphoSitePlus
S902 Phosphorylation PhosphoSitePlus
S907 Phosphorylation PhosphoSitePlus
K927 Ubiquitination PhosphoSitePlus
S952 O-Glycosylation GlyGen 23301498, 33214551, 32574038, ...30059200, 30620550, 34019948, 31492838, 35289036, 35254053, 29237092, 20068230
S1013 Phosphorylation PhosphoSitePlus
K1030 Ubiquitination PhosphoSitePlus
K1037 Sumoylation PhosphoSitePlus
K1037 Ubiquitination PhosphoSitePlus
S1045 Phosphorylation PhosphoSitePlus
T1049 Phosphorylation PhosphoSitePlus
S1055 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 15302935, ...18669648, 24275569
T1057 Phosphorylation PhosphoSitePlus
S1077 Phosphorylation PhosphoSitePlus
S1086 Phosphorylation PhosphoSitePlus
S1087 Phosphorylation PhosphoSitePlus
K1098 Ubiquitination PhosphoSitePlus
K1100 Ubiquitination PhosphoSitePlus
K1115 Sumoylation PhosphoSitePlus
R1139 Methylation PhosphoSitePlus
K1148 Ubiquitination PhosphoSitePlus
K1153 Sumoylation PhosphoSitePlus
S1188 O-Glycosylation GlyGen 32574038
T1195 O-Glycosylation GlyGen 23301498, 33214551, 32574038, ...30059200, 30620550, 34019948, 31492838, 35289036, 35254053, 29237092, 20068230
S1196 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 33214551, 32574038, ...30059200, 30620550, 34019948, 31492838, 35289036, 35254053, 29237092, 20068230
S1199 O-Glycosylation GlyGen 23301498, 33214551, 32574038, ...30059200, 30620550, 34019948, 31492838, 35289036, 35254053, 29237092, 20068230
S1232 O-Glycosylation GlyGen 32574038
S1285 Phosphorylation PhosphoSitePlus
K1297 Ubiquitination PhosphoSitePlus
K1310 Ubiquitination PhosphoSitePlus
S1311 Phosphorylation PhosphoSitePlus
S1313 Phosphorylation PhosphoSitePlus
R1410 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S23 Phosphorylation HPRD 18452278
S125 Phosphorylation HPRD 20068231
S274 Phosphorylation HPRD 18452278
S358 Phosphorylation HPRD 18669648, 19664995, 20068231, ...18452278
T360 Phosphorylation HPRD 20068231
S361 Phosphorylation HPRD 20068231
T381 Phosphorylation HPRD 19413330
S413 Phosphorylation HPRD 18452278
S425 Phosphorylation HPRD 17081983
T465 Phosphorylation HPRD 19664995, 20068231
S467 Phosphorylation HPRD 19413330, 18767875, 18669648, ...19651622
S470 Phosphorylation HPRD 19413330, 20068231
T483 Phosphorylation HPRD 20068231
S560 Phosphorylation HPRD 19413330
T566 Phosphorylation HPRD 19413330
S576 Phosphorylation HPRD 16964243, 19664995, 18452278, ...19651622, 18669648, 19415658, 20068231, 17081983
S578 Phosphorylation HPRD 17081983, 19651622, 18669648, ...19415658, 20068231, 16964243
S580 Phosphorylation HPRD 19651622, 17081983
S581 Phosphorylation HPRD 19651622, 17081983, 20068231
T709 Phosphorylation HPRD 20068231
S743 Phosphorylation HPRD 19651622, 20068231
T746 Phosphorylation HPRD 19413330, 19651622, 19664994, ...19664995, 20068231
S758 Phosphorylation HPRD 19651622, 18212344
S804 Phosphorylation HPRD 19413330, 18669648, 19664995, ...20068231
S806 Phosphorylation HPRD 18669648, 20068231
T816 Phosphorylation HPRD 20068231
T823 Phosphorylation HPRD 20068231
T840 Phosphorylation HPRD 18669648
S842 Phosphorylation HPRD 19413330, 17081983, 18452278, ...19651622, 18669648, 16964243
Y845 Phosphorylation HPRD 19413330, 18669648
S846 Phosphorylation HPRD 19413330, 19651622, 18669648, ...16964243, 17081983
S849 Phosphorylation HPRD 19413330, 19651622, 18669648, ...17081983
T1049 Phosphorylation HPRD 18452278
S1055 Phosphorylation HPRD 19413330, 18669648, 19664994, ...19664995
S1077 Phosphorylation HPRD 20068231
Y1244 Phosphorylation HPRD 20068231
S1262 Phosphorylation HPRD 20068231
S1267 Phosphorylation HPRD 20068231
Y1269 Phosphorylation HPRD 20068231
S1271 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S8 C8 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S95 R95 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S107 F107 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S125 P125 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S165 C165 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S165 F165 Biomuta DOID:4159 / skin cancer [ cosmic, icgc, tcga ]
S433 G433 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S446 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S560 F560 Biomuta [ cosmic ]
S581 N581 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S738 L738 Biomuta DOID:4159 / skin cancer [ cosmic ]
S743 N743 Biomuta DOID:363 / uterine cancer [ icgc ]
T799 M799 Biomuta DOID:3571 / liver cancer [ cosmic ]
S849 F849 Biomuta [ cosmic ]
K1100 R1100 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K1100 N1100 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T1195 M1195 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1232 F1232 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1267 F1267 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1285 N1285 Biomuta [ cosmic ]
K1310 N1310 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R1410 G1410 Biomuta DOID:2531 / hematologic cancer [ cosmic ]