Protein Information

Cytoscape View


UniProt AC / UniProt ID O14933 / UB2L6_HUMAN
Protein Name Ubiquitin/ISG15-conjugating enzyme E2 L6
Gene Name Name: UBE2L6
Synonyms:UBCH8;
Organism Homo sapiens (Human)

PRO ID PR:O14933
DAG View
PRO Name ubiquitin/ISG15-conjugating enzyme E2 L6 (human)
Definition A ubiquitin/ISG15-conjugating enzyme E2 L6 that is encoded in the genome of human.
Short Label hUBE2L6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O14933 (UBE2L6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K9 Ubiquitination PhosphoSitePlus
K17 Ubiquitination PhosphoSitePlus
S26 Phosphorylation PhosphoSitePlus
C86 Methylation IEDB 31844290
K96 Ubiquitination PhosphoSitePlus
K138 Acetylation PhosphoSitePlus
K138 Ubiquitination PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C86 R86 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
C86 * Biomuta [ cosmic ]