iPTMnet Report for O14787 (TNPO2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O14787 / TNPO2_HUMAN
Protein Name Transportin-2
Gene Name Name: TNPO2
Organism Homo sapiens (Human)

PRO ID PR:O14787
DAG View
PRO Name transportin-2 (human)
Definition A transportin-2 that is encoded in the genome of human.
Short Label hTNPO2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O14787 (TNPO2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T25 Phosphorylation PhosphoSitePlus
K34 Ubiquitination PhosphoSitePlus
S57 Phosphorylation PhosphoSitePlus
S64 Phosphorylation PhosphoSitePlus
S66 Phosphorylation PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
K75 Ubiquitination PhosphoSitePlus
Y258 Phosphorylation PhosphoSitePlus
K334 Ubiquitination PhosphoSitePlus
S355 Phosphorylation PhosphoSitePlus
K374 Ubiquitination PhosphoSitePlus
K484 Ubiquitination PhosphoSitePlus
C498 Methylation IEDB 31844290
C509 Methylation IEDB 31844290
C805 Methylation IEDB 31844290
K817 Ubiquitination PhosphoSitePlus
K862 Acetylation PhosphoSitePlus   UniProt 19608861
K862 Ubiquitination PhosphoSitePlus
K868 Ubiquitination PhosphoSitePlus
K888 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S355 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S57 * Biomuta DOID:1612 / breast cancer [ cosmic ]
K71 N71 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K374 E374 Biomuta DOID:3571 / liver cancer [ cosmic ]