iPTMnet Report for O14757 (CHEK1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O14757 / CHK1_HUMAN
Protein Name Serine/threonine-protein kinase Chk1
Gene Name Name: CHEK1
Synonyms:CHK1;
Organism Homo sapiens (Human)

PRO ID PR:O14757
DAG View
PRO Name serine/threonine-protein kinase Chk1 (human)
Definition A serine/threonine-protein kinase Chk1 that is encoded in the genome of human.
Short Label hCHEK1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O14757 (CHEK1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T14 Phosphorylation RLIMS-P 33513721, 21965652
K43 Ubiquitination PhosphoSitePlus
K53 Acetylation PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus   UniProt 32357935
K145 Ubiquitination PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
K180 Ubiquitination PhosphoSitePlus
K225 Ubiquitination PhosphoSitePlus
K233 Ubiquitination PhosphoSitePlus
K244 Ubiquitination PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
T279 Phosphorylation PhosphoSitePlus
S280 Phosphorylation Q15418 (RPS6KA1) , P11309 (PIM1) , P31749 (AKT1) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P+   RLIMS-P   Signor   UniProt 17495959, 29500400, 22505024, ...30100999, 23186163, 15710331, 12062056, 23748345, 30428154, 33007920, 26091525, 19421147, 26675484, 22357623, 17418864, 29976560, 18669648, 26295308, 24525237, 23108403, 15107605
S284 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P 30428154, 18669648
S286 Phosphorylation P24941 (CDK2) , P06493 (CDK1) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P+   RLIMS-P   Signor   UniProt 19837665, 21765472, 16629900, ...18669648, 20068231, 18983824
S288 Phosphorylation PhosphoSitePlus
S291 Phosphorylation O14757 (CHEK1) PhosphoSitePlus 21851590
K292 Ubiquitination PhosphoSitePlus
S296 Phosphorylation O14757 (CHEK1) , Q13535 (ATR) IntAct   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 25104095, 23068608, 26542114, ...23082860, 20639859, 31316063, 23597309, 29221122, 22623962, 30119887, 29500400, 33591599, 20053681, 24753408, 15975956, 24913641, 25217585, 27829224, 30001349, 25474241, 23186163, 29162833, 24359526, 26595527, 28042876, 29118324, 32610557, 30837643, 25249630, 32533099, 24894074, 29617433, 24996846, 32076484, 25460505, 22957056, 15707391, 25904336, 30100999, 25283841, 23755068, 19401701, 22357623, 32901871, 32579780, 24928205, 21289283, 32294924, 19369195, 25527123, 28106079, 29152060, 26271993, 29340034, 25301724, 26437226, 26867682, 24804719, 32647134, 27775084, 18669648, 26295308, 25884494, 19351595, 28888100, 31209037, 20053762, 20068231, 28915668
S301 Phosphorylation P24941 (CDK2) , P06493 (CDK1) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P+   RLIMS-P   Signor   UniProt 18691976, 23186163, 19837665, ...28035370, 21765472, 16629900, 18669648, 19690332, 20068231, 18983824
S305 Phosphorylation PhosphoSitePlus
S307 Phosphorylation PhosphoSitePlus
S308 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
K313 Ubiquitination PhosphoSitePlus
S315 Phosphorylation PhosphoSitePlus
S316 Phosphorylation O14757 (CHEK1) PhosphoSitePlus 21851590
S317 Phosphorylation Q13535 (ATR) , Q13315 (ATM) neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P+   RLIMS-P   Signor   UniProt 22686412, 29383140, 20194642, ...18955550, 18247328, 22743332, 17242188, 29118324, 19390600, 32357935, 12676583, 26114388, 12676962, 23396447, 30337689, 15707391, 32533099, 19421147, 25593194, 26057167, 21440578, 33101488, 18272544, 27940557, 32847043, 25249630, 29340034, 29725502, 23383325, 20373286, 19091954, 16293623, 25217585, 25301724, 23597309, 25965828, 18723495, 15870257, 24913641, 25474241, 11252893, 26860083, 32042960, 22977173, 21870291, 26161259, 12588868, 24996846, 32076484, 25460505, 32591500, 30237520, 30439567, 31209037, 26714930, 32647134, 27775084, 24376897, 26295308, 33477536, 30384048, 25104095, 26658951, 18353973, 23874235, 33020410, 32085572, 31044505, 17525332, 21390062, 17015476, 11390642, 15775976, 20195506, 29617433, 25565400, 14657349, 25904336, 30100999, 19459175, 10859164, 23220466, 21347609, 29963769, 26271993, 27029031, 24753408, 35889508, 18669648, 19351595, 30796221, 28915668, 12446774, 32210727, 26542114, 26439697, 24244353, 12660173, 22623962, 24500207, 25283841, 18787399, 16456034, 17912033, 22855742, 18166648, 22319212, 20440263, 25216266, 20068082, 19625493, 16629900, 27538817, 21851590, 25916848
T330 Phosphorylation PhosphoSitePlus
S331 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S333 Phosphorylation PhosphoSitePlus
S343 Phosphorylation PhosphoSitePlus   RLIMS-P 21390062
S345 Phosphorylation Q13535 (ATR) , P41279 (MAP3K8) , Q13315 (ATM) IntAct   neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 20479464, 29383140, 22768280, ...31717700, 27558808, 29464074, 21321020, 12370755, 31316063, 26039276, 29221122, 32628111, 27888802, 19716789, 29074359, 16461339, 18955550, 31209037, 18247328, 21965652, 28264028, 24359526, 17242188, 29118324, 15190204, 27685627, 32357935, 19541796, 26114388, 12676962, 31759252, 17982623, 17634129, 20976184, 26919204, 19421147, 24023735, 26057167, 21440578, 33101488, 22357623, 31805725, 19804365, 27940557, 31431503, 24260532, 24505404, 32859084, 29340034, 26271993, 15533933, 23383325, 19464357, 20373286, 28049532, 23148684, 21593792, 22761726, 29163782, 22937147, 26441204, 21777809, 19261750, 22623962, 23597309, 17495959, 20068082, 30510197, 30119887, 24005565, 24913641, 20609246, 25474241, 16414131, 15322239, 27643582, 19411857, 31362447, 15674326, 26860083, 32042960, 30837643, 11553781, 21870291, 32085572, 26161259, 15775976, 14988723, 31285446, 24996846, 25460505, 33820915, 19351595, 19477925, 26748709, 19139065, 28415748, 33087136, 11896572, 25486478, 20679434, 30516086, 31017975, 27603133, 28967905, 25336189, 24153426, 31164689, 32647134, 32545536, 26295308, 15650047, 25904336, 18071310, 30657978, 12684226, 33477536, 15107605, 30384048, 25301724, 25104095, 24758542, 12446774, 25700705, 20639859, 32294924, 18353973, 23874235, 27472395, 27286446, 24204313, 28535155, 31832331, 33020410, 26684013, 30211163, 33546122, 18983824, 32276518, 33168956, 24753408, 12959929, 28042876, 29725502, 25249630, 11390642, 19646247, 12676583, 17638905, 29617433, 12676925, 25565400, 17015476, 20195506, 25283841, 24309929, 33870196, 28986587, 19330022, 25527123, 28573382, 25316620, 30900384, 21289283, 29092815, 30237857, 33556369, 29963769, 16137618, 26312135, 24260231, 27286453, 30445466, 26438152, 30543688, 30337689, 28558031, 25884494, 25016522, 23852422, 20840867, 23897887, 28915668, 31302002, 32210727, 29741650, 26542114, 24244353, 23755068, 10859164, 14681223, 15707391, 33466733, 28180282, 25375241, 23861943, 30100999, 33657372, 21730979, 18787399, 15870257, 18495871, 27401717, 25880358, 24182986, 22855742, 31114910, 17236549, 13679850, 19855428, 19401701, 29444163, 26208482, 23799366, 29069457, 32591500, 27271602, 32579780, 28025997, 28881656, 24812435, 30889383, 29242514, 16629900, 12150968, 17210576, 24853431, 21851590, 19177015, 19828454, 25916848
T348 Phosphorylation PhosphoSitePlus
C349 Methylation IEDB 31844290
S357 Phosphorylation PhosphoSitePlus
T362 Phosphorylation PhosphoSitePlus
S365 Phosphorylation PhosphoSitePlus
S366 Phosphorylation PhosphoSitePlus   RLIMS-P 19421147
T378 Phosphorylation PhosphoSitePlus   RLIMS-P 30510197
T382 Phosphorylation PhosphoSitePlus   RLIMS-P 30510197
K383 Ubiquitination PhosphoSitePlus
K388 Ubiquitination PhosphoSitePlus
S389 Phosphorylation PhosphoSitePlus
K399 Ubiquitination PhosphoSitePlus
S407 Phosphorylation PhosphoSitePlus
C408 Methylation IEDB 31844290
T417 O-Glycosylation GlyGen 30379171
K423 Ubiquitination PhosphoSitePlus
K436 Ubiquitination PhosphoSitePlus   UniProt 19716789
K445 Ubiquitination PhosphoSitePlus
K452 Acetylation PhosphoSitePlus
K452 Ubiquitination PhosphoSitePlus
K461 Ubiquitination PhosphoSitePlus
S467 Phosphorylation IEDB   PhosphoSitePlus   UniProt 23186163, 32357974
S468 Phosphorylation PhosphoSitePlus   UniProt 23186163
Site PTM Type PTM Enzyme Score Source PMID
T279 Phosphorylation HPRD 19413330, 18691976, 20068231
S280 Phosphorylation P31749 (AKT1) HPRD 12062056, 18691976, 18669648, ...19664995, 20068231
S284 Phosphorylation HPRD 19413330, 18691976, 18669648
S286 Phosphorylation HPRD 19413330, 18691976, 18669648, ...20068231
S288 Phosphorylation HPRD 20068231
S296 Phosphorylation HPRD 18669648, 20068231
S301 Phosphorylation HPRD 19651622, 18691976, 18669648, ...20068231
S305 Phosphorylation HPRD 18691976
S307 Phosphorylation HPRD 18691976
S308 Phosphorylation HPRD 18691976, 17525332
S317 Phosphorylation Q13535 (ATR) HPRD 18691976, 18669648, 11252893, ...15665856, 11390642
T330 Phosphorylation HPRD 18691976
S331 Phosphorylation HPRD 18691976, 18669648, 20068231
S345 Phosphorylation Q13535 (ATR) HPRD 15665856, 11390642
S468 Phosphorylation HPRD 18691976, 20068231


O14757 (CHEK1) as PTM Enzyme



Substrate Site Score Source PMID
O00716 (E2F3) S124 PhosphoSitePlus   Signor 19917728
O14757 (CHEK1) S291 PhosphoSitePlus 21851590
O14757 (CHEK1) S296 PhosphoSitePlus   Signor 20639859, 22357623, 23068608
O14757 (CHEK1) S316 PhosphoSitePlus 21851590
O15151 (MDM4) S342 HPRD   PhosphoSitePlus   Signor 16163388
O15151-1 (MDM4) S367 HPRD   neXtProt   PhosphoSitePlus   Signor 18356162, 17110929, 16511572, ...16163388
O15294 (OGT) S20 PhosphoSitePlus 21851590
O15350 (TP73) S47 PhosphoSitePlus   Signor 14585975
O43395 (PRPF3) S161 PhosphoSitePlus 21851590
O43660 (PLRG1) S119 PhosphoSitePlus 21851590
O60343 (TBC1D4) S485 PhosphoSitePlus 21851590
O60343 (TBC1D4) S588 PhosphoSitePlus 21851590
O75151 (PHF2) S929 PhosphoSitePlus 21851590
O75461 (E2F6) S12 PhosphoSitePlus 23954429
O75461 (E2F6) S52 PhosphoSitePlus 23954429
O95625 (ZBTB11) S511 PhosphoSitePlus 21851590
O95625 (ZBTB11) S537 PhosphoSitePlus 21851590
O95707 (POP4) S10 PhosphoSitePlus 21851590
O95785 (WIZ) S1129 PhosphoSitePlus 21851590
P02545 (LMNA) S307 PhosphoSitePlus 21851590
P04637 (TP53) S15 HPRD   PhosphoSitePlus   Signor 15659650, 10673501, 11709713, ...11551930, 9765199, 12756247
P04637 (TP53) T18 PhosphoSitePlus   Signor 17339337, 15659650
P04637 (TP53) S20 HPRD   PhosphoSitePlus   RLIMS-P+   Signor 15659650, 15467443, 10673501, ...11709713, 17339337, 11551930
P04637 (TP53) S37 HPRD   PhosphoSitePlus   Signor 10673501, 11709713, 12756247, ...15659650
P04637 (TP53) S366 Signor 15659650
P04637 (TP53) S378 PhosphoSitePlus   Signor 15659650
P04637 (TP53) T387 PhosphoSitePlus   Signor 15659650
P06400 (RB1) S612 PhosphoSitePlus   Signor 17380128
P06493 (CDK1) S208 PhosphoSitePlus 21851590
P07814 (EPRS1) S910 PhosphoSitePlus 21851590
P10636-8 (MAPT) S262 PhosphoSitePlus 20159774
P11047 (LAMC1) T258 PhosphoSitePlus 21851590
P12956 (XRCC6) S477 PhosphoSitePlus 21851590
P15822 (HIVEP1) S1749 PhosphoSitePlus 21851590
P16989 (YBX3) T112 PhosphoSitePlus 21851590
P18858 (LIG1) S76 PhosphoSitePlus 21851590
P19838 (NFKB1) S328 PhosphoSitePlus   Signor 22152481
P22626 (HNRNPA2B1) T159 PhosphoSitePlus 21851590
P25205 (MCM3) S160 PhosphoSitePlus 25809478
P26373 (RPL13) T170 PhosphoSitePlus 21851590
P27816 (MAP4) T925 PhosphoSitePlus 21851590
P30304 (CDC25A) S76 PhosphoSitePlus   RLIMS-P+   Signor 18167338, 18480045, 12759351, ...21252624, 20068082, 14681206, 20639859
P30304 (CDC25A) S124 HPRD   PhosphoSitePlus   Signor 20068082, 12399544, 12676583, ...12759351
P30304 (CDC25A) S178 HPRD   PhosphoSitePlus   Signor 20068082, 12759351, 12676583, ...14559997
P30304-2 (CDC25A) S239 HPRD 12676583
P30304-2 (CDC25A) S253 HPRD 12676583
P30304 (CDC25A) S279 HPRD   PhosphoSitePlus   Signor 20068082, 12676583
P30304-1 (CDC25A) S293 HPRD   PhosphoSitePlus   Signor 20068082, 12676583
P30304 (CDC25A) T507 PhosphoSitePlus   Signor 20068082, 20639859, 14559997
P30305 (CDC25B) S230 PhosphoSitePlus   Signor 17003105
P30305 (CDC25B) S563 PhosphoSitePlus 17003105
P30307 (CDC25C) S216 HPRD   neXtProt   PhosphoSitePlus   RLIMS-P+   Signor 25809478, 10681541, 10391675, ...9543386, 20068082, 9836640, 10557092, 9278511, 14681223, 12766774, 9278512, 11333986, 11551930, 10786669, 20068231
P33992 (MCM5) T633 PhosphoSitePlus 21851590
P35611 (ADD1) S726 PhosphoSitePlus 21851590
P35612 (ADD2) S713 PhosphoSitePlus 21851590
P36507 (MAP2K2) T59 PhosphoSitePlus 21851590
P38936 (CDKN1A) T145 RLIMS-P+ 25486478
P38936 (CDKN1A) S146 RLIMS-P+ 25486478
P39748 (FEN1) T195 PhosphoSitePlus 21851590
P43243 (MATR3) S4 PhosphoSitePlus 21851590
P43243 (MATR3) T150 PhosphoSitePlus 21851590
P43243 (MATR3) S195 PhosphoSitePlus 21851590
P43405 (SYK) S295 PhosphoSitePlus   Signor 22585575
P46013 (MKI67) T1764 PhosphoSitePlus 21851590
P49761 (CLK3) S157 PhosphoSitePlus 21851590
P49790 (NUP153) S297 PhosphoSitePlus 21851590
P49790 (NUP153) S330 PhosphoSitePlus 21851590
P49792 (RANBP2) T1098 PhosphoSitePlus 21851590
P52272 (HNRNPM) S432 PhosphoSitePlus 21851590
P52292 (KPNA2) S54 PhosphoSitePlus 21851590
P52294 (KPNA1) S18 PhosphoSitePlus 21851590
P54132 (BLM) T182 PhosphoSitePlus 26028025
P54132 (BLM) S539 PhosphoSitePlus 21851590
P54132 (BLM) S646 PhosphoSitePlus   Signor 20719863
P55039 (DRG2) S72 PhosphoSitePlus 21851590
P67809 (YBX1) T80 PhosphoSitePlus 21851590
P67870 (CSNK2B) T213 PhosphoSitePlus 15225637
P68431 (H3C12) T12 neXtProt 18243098
P84098 (RPL19) S12 PhosphoSitePlus 21851590
P84098 (RPL19) T56 PhosphoSitePlus 21851590
P84243 (H3-3B) T12 Signor 18243098
P85299 (PRR5) S240 PhosphoSitePlus 21851590
Q00341 (HDLBP) T8 PhosphoSitePlus 21851590
Q02750 (MAP2K1) T55 PhosphoSitePlus 21851590
Q04837 (SSBP1) S67 PhosphoSitePlus 21851590
Q06609-1 (RAD51) T309 HPRD   Signor 15665856
Q08AD1 (CAMSAP2) S464 PhosphoSitePlus 21851590
Q12789 (GTF3C1) S667 PhosphoSitePlus 21851590
Q12888 (TP53BP1) S1678 PhosphoSitePlus 21851590
Q13043 (STK4) T340 PhosphoSitePlus 21851590
Q13257 (MAD2L1) S185 PhosphoSitePlus 23454898
Q13257 (MAD2L1) T187 PhosphoSitePlus 23454898
Q13263 (TRIM28) S473 PhosphoSitePlus   RLIMS-P+ 21851590, 22496453
Q13439 (GOLGA4) S71 PhosphoSitePlus 21851590
Q13470 (TNK1) S502 PhosphoSitePlus 21851590
Q13907 (IDI1) S55 PhosphoSitePlus 21851590
Q14004 (CDK13) S437 PhosphoSitePlus 21851590
Q14186 (TFDP1) S23 PhosphoSitePlus 21851590
Q14247 (CTTN) S298 PhosphoSitePlus 21851590
Q14669 (TRIP12) S1078 PhosphoSitePlus 21851590
Q14676 (MDC1) T523 PhosphoSitePlus 21851590
Q14738 (PPP2R5D) S60 PhosphoSitePlus 17110335
Q14966 (ZNF638) S375 PhosphoSitePlus 21851590
Q15648 (MED1) T704 PhosphoSitePlus 21851590
Q16143 (SNCB) Y127 PhosphoSitePlus   Signor 21699177
Q16181 (SEPTIN7) T228 PhosphoSitePlus 21851590
Q16204 (CCDC6) S240 PhosphoSitePlus 21851590
Q16204 (CCDC6) S244 PhosphoSitePlus 21851590
Q27J81 (INF2) S574 PhosphoSitePlus 21851590
Q32P44 (EML3) S176 PhosphoSitePlus 21851590
Q53F19 (NCBP3) S100 PhosphoSitePlus 21851590
Q53H47 (SETMAR) S508 PhosphoSitePlus   Signor 22231448, 25024738
Q5JSZ5 (PRRC2B) S166 PhosphoSitePlus 21851590
Q5JTH9 (RRP12) S1049 PhosphoSitePlus 21851590
Q5T8P6 (RBM26) T839 PhosphoSitePlus 21851590
Q5UIP0 (RIF1) S2205 PhosphoSitePlus 21851590
Q6PD62 (CTR9) S1081 PhosphoSitePlus 21851590
Q6T4R5 (NHS) T401 PhosphoSitePlus 21851590
Q6UB98-2 (ANKRD12) S76 PhosphoSitePlus 21851590
Q7Z2Z1 (TICRR) S865 PhosphoSitePlus 21851590
Q7Z2Z1 (TICRR) S1045 PhosphoSitePlus 21851590
Q7Z2Z1 (TICRR) S1894 PhosphoSitePlus 25557548
Q7Z2Z1 (TICRR) T1898 PhosphoSitePlus 25557548
Q86UE8 (TLK2) S686 PhosphoSitePlus 21851590
Q86UE8 (TLK2) S750 neXtProt 12955071
Q86WB0 (ZC3HC1) T84 PhosphoSitePlus 21851590
Q86WR7 (PROSER2) S43 PhosphoSitePlus 21851590
Q8IY67-2 (RAVER1) S700 PhosphoSitePlus 21851590
Q8N4C8 (MINK1) T280 PhosphoSitePlus 21851590
Q8NG66 (NEK11) S273 neXtProt   PhosphoSitePlus   Signor 19734889
Q8WWI1 (LMO7) S1510 PhosphoSitePlus 21851590
Q92974 (ARHGEF2) S172 PhosphoSitePlus 21851590
Q96E09 (PABIR1) S37 Signor 33108758
Q96GD4 (AURKB) S331 PhosphoSitePlus   Signor 17276342, 22024163
Q96PK6 (RBM14) S618 PhosphoSitePlus 21851590
Q96PK6 (RBM14) S627 PhosphoSitePlus 21851590
Q96PK6 (RBM14) T629 PhosphoSitePlus 21851590
Q96QD9 (FYTTD1) T205 PhosphoSitePlus 21851590
Q96RL1 (UIMC1) S627 PhosphoSitePlus 21851590
Q96ST3 (SIN3A) T434 PhosphoSitePlus 21851590
Q96T58 (SPEN) T1059 PhosphoSitePlus 21851590
Q99590 (SCAF11) S1127 PhosphoSitePlus 21851590
Q99848 (EBNA1BP2) T182 PhosphoSitePlus 21851590
Q9BQG0 (MYBBP1A) S1310 PhosphoSitePlus 21851590
Q9BRD0 (BUD13) S18 PhosphoSitePlus 21851590
Q9BTD8 (RBM42) S406 PhosphoSitePlus 21851590
Q9BW19 (KIFC1) S26 PhosphoSitePlus 21851590
Q9BXB4 (OSBPL11) S189 PhosphoSitePlus 21851590
Q9BXW9 (FANCD2) S331 neXtProt   PhosphoSitePlus   Signor 19861535
Q9BY77 (POLDIP3) S63 PhosphoSitePlus 21851590
Q9GZR7 (DDX24) S82 PhosphoSitePlus 21851590
Q9H0H5 (RACGAP1) S203 PhosphoSitePlus 21851590
Q9H8G2 (CAAP1) S203 PhosphoSitePlus 21851590
Q9H8N7 (ZNF395) S447 PhosphoSitePlus 21851590
Q9HAW4 (CLSPN) T916 HPRD   neXtProt   PhosphoSitePlus   Signor 16963448
Q9HB96 (FANCE) T346 neXtProt   PhosphoSitePlus   Signor 17296736
Q9HB96 (FANCE) S374 neXtProt   PhosphoSitePlus   Signor 17296736
Q9HC62 (SENP2) S344 PhosphoSitePlus 21851590
Q9NRL2 (BAZ1A) S1320 PhosphoSitePlus 21851590
Q9NRM7 (LATS2) S172 neXtProt 21118956, 23886938
Q9NRM7 (LATS2) S380 neXtProt 21118956, 23886938
Q9NRM7 (LATS2) S408 neXtProt   PhosphoSitePlus 21118956, 23886938
Q9NRM7 (LATS2) S446 neXtProt 21118956, 23886938
Q9NRM7 (LATS2) S835 neXtProt   PhosphoSitePlus 21118956, 23886938
Q9NS23-2 (RASSF1) T38 PhosphoSitePlus 24197116
Q9NS23-2 (RASSF1) T43 PhosphoSitePlus 24197116
Q9NS23-2 (RASSF1) S184 PhosphoSitePlus 24197116
Q9NS23 (RASSF1) S188 Signor 24197116
Q9NUU7 (DDX19A) S92 PhosphoSitePlus 21851590
Q9NWH9 (SLTM) S748 PhosphoSitePlus 21851590
Q9NWH9 (SLTM) S815 PhosphoSitePlus 21851590
Q9NXE8 (CWC25) S337 PhosphoSitePlus 21851590
Q9P2D1 (CHD7) T1227 PhosphoSitePlus 21851590
Q9UEY8 (ADD3) S693 PhosphoSitePlus 21851590
Q9UJM3 (ERRFI1) S251 neXtProt   PhosphoSitePlus 22505024
Q9UJM3 (ERRFI1) S302 PhosphoSitePlus 22505024
Q9UK53-2 (ING1) S126 PhosphoSitePlus 17585055
Q9UKI8-2 (TLK1) S700 PhosphoSitePlus 21851590
Q9UKI8 (TLK1) S743 HPRD   neXtProt   Signor 12955071, 18669648, 20581459, ...20068231, 12660173
Q9UKI8-2 (TLK1) S764 PhosphoSitePlus 12660173
Q9UKM9 (RALY) T160 PhosphoSitePlus 21851590
Q9UMR2 (DDX19B) S93 PhosphoSitePlus 21851590
Q9UPP1 (PHF8) S904 PhosphoSitePlus 21851590
Q9UQ35 (SRRM2) S1497 PhosphoSitePlus 21851590
Q9UQ35 (SRRM2) S1499 PhosphoSitePlus 21851590
Q9UQ35 (SRRM2) T2252 PhosphoSitePlus 21851590
Q9UQ35 (SRRM2) S2280 PhosphoSitePlus 21851590
Q9UQ35 (SRRM2) S2388 PhosphoSitePlus 21851590
Q9Y2T7 (YBX2) T115 PhosphoSitePlus 21851590
Q9Y3Y2 (CHTOP) T212 PhosphoSitePlus 21851590
Q9Y4F5 (CEP170B) S655 PhosphoSitePlus 21851590
Q9Y520 (PRRC2C) S661 PhosphoSitePlus 21851590
Q9Y570 (PPME1) S15 PhosphoSitePlus 21851590


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000046701 (hCHEK1/Phos:2) pS317,pS345 PRO


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation O14757 (CHEK1) S345 P54252 (ATXN3) unknown eFIP 28180282
Phosphorylation O14757 (CHEK1) S296 P30304 (CDC25A) unknown eFIP 20639859
Phosphorylation P30304 (CDC25A) T507 O14757 (CHEK1) unknown eFIP 14559997