iPTMnet Report for O14638 (ENPP3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O14638 / ENPP3_HUMAN
Protein Name Ectonucleotide pyrophosphatase/phosphodiesterase family member 3
Gene Name Name: ENPP3
Synonyms:PDNP3;
Organism Homo sapiens (Human)

PRO ID PR:O14638
DAG View
PRO Name ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (human)
Definition An ectonucleotide pyrophosphatase/phosphodiesterase family member 3 that is encoded in the genome of human.
Short Label hENPP3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O14638 (ENPP3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T205 Phosphorylation PhosphoSitePlus 7505270
T205 Phosphorylation O14638 (ENPP3) PhosphoSitePlus 7505270
N236 N-Glycosylation GlyGen   UniProt 29717535
N279 N-Glycosylation GlyGen   UniProt 29717535
N290 N-Glycosylation GlyGen   UniProt 29717535
Y389 Phosphorylation PhosphoSitePlus
N426 N-Glycosylation GlyGen   UniProt 29717535
N532 N-Glycosylation GlyGen 24190977
N533 N-Glycosylation GlyGen   UniProt 29717535, 24190977
N540 N-Glycosylation GlyGen 24190977
N582 N-Glycosylation GlyGen   UniProt 29717535
N594 N-Glycosylation GlyGen   UniProt 29717535
N687 N-Glycosylation GlyGen   UniProt 29717535, 24190977
T689 Phosphorylation PhosphoSitePlus
Y694 Phosphorylation PhosphoSitePlus
N699 N-Glycosylation GlyGen   UniProt 29717535, 24190977
N789 N-Glycosylation GlyGen   UniProt 29717535
T846 Phosphorylation PhosphoSitePlus
Y851 Phosphorylation PhosphoSitePlus


O14638 (ENPP3) as PTM Enzyme



Substrate Site Score Source PMID
O14638 (ENPP3) T205 PhosphoSitePlus 7505270


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T205 I205 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
N533 H533 Biomuta DOID:363 / uterine cancer [ icgc ]
N699 S699 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
N789 D789 Biomuta DOID:10283 / prostate cancer [ cosmic ]
N789 S789 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]