iPTMnet Report for O14545 (TRAFD1)
Protein Information
UniProt AC / UniProt ID | O14545 / TRAD1_HUMAN |
Protein Name | TRAF-type zinc finger domain-containing protein 1 |
Gene Name | Name: TRAFD1 Synonyms:FLN29; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O14545 |
PRO Name | TRAF-type zinc finger domain-containing protein 1 (human) |
Definition | A TRAF-type zinc finger domain-containing protein 1 that is encoded in the genome of human. |
Short Label | hTRAFD1 |
Category | organism-gene |
O14545 (TRAFD1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 22814378 | ||
C32 | Methylation | score1 | IEDB | 31844290 | ||
K43 | Ubiquitination | score1 | PhosphoSitePlus | |||
K65 | Ubiquitination | score1 | PhosphoSitePlus | |||
K77 | Ubiquitination | score1 | PhosphoSitePlus | |||
C93 | Methylation | score1 | IEDB | 31844290 | ||
S98 | Phosphorylation | score1 | PhosphoSitePlus | |||
K103 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y108 | Phosphorylation | score1 | PhosphoSitePlus | |||
C109 | Methylation | score1 | IEDB | 31844290 | ||
K126 | Ubiquitination | score1 | PhosphoSitePlus | |||
K129 | Ubiquitination | score1 | PhosphoSitePlus | |||
S191 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S209 | Phosphorylation | score1 | PhosphoSitePlus | |||
C267 | Methylation | score1 | IEDB | 31844290 | ||
S272 | Phosphorylation | score1 | PhosphoSitePlus | |||
S278 | O-Glycosylation | score1 | GlyGen | 30379171, 29351928 | ||
S278 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S320 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
T323 | Phosphorylation | score1 | PhosphoSitePlus | |||
S325 | Phosphorylation | score1 | PhosphoSitePlus | |||
S326 | O-Glycosylation | score1 | GlyGen | 30379171, 29351928 | ||
S326 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 21406692 | ||
S327 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 23186163, 16964243, ... | ||
S409 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 24275569 | ||
T414 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S415 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 23186163, 16964243, ... | ||
S430 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
Y433 | Phosphorylation | score1 | PhosphoSitePlus | |||
S470 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
S479 | Phosphorylation | score1 | PhosphoSitePlus | |||
S480 | Phosphorylation | score1 | PhosphoSitePlus | |||
K485 | Ubiquitination | score1 | PhosphoSitePlus | |||
S487 | Phosphorylation | score1 | PhosphoSitePlus | |||
S491 | Phosphorylation | score1 | PhosphoSitePlus | |||
S501 | Phosphorylation | score2 | IEDB PhosphoSitePlus | 35494241 | ||
S530 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
Y537 | Phosphorylation | score1 | PhosphoSitePlus | |||
S540 | Phosphorylation | score1 | PhosphoSitePlus | |||
S543 | Phosphorylation | score1 | PhosphoSitePlus | |||
S549 | Phosphorylation | score1 | PhosphoSitePlus | |||
T552 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y558 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S320 | Phosphorylation | score0 | HPRD | 18212344 | ||
T323 | Phosphorylation | score0 | HPRD | 17081983, 19691289, 19664995, ... | ||
S325 | Phosphorylation | score0 | HPRD | 19651622, 18691976, 20058876, ... | ||
S326 | Phosphorylation | score0 | HPRD | 18691976, 18669648, 19664995, ... | ||
S327 | Phosphorylation | score0 | HPRD | 19413330, 18691976, 16964243, ... | ||
S409 | Phosphorylation | score0 | HPRD | 20068231 | ||
T414 | Phosphorylation | score0 | HPRD | 18691976, 17081983, 20230923, ... | ||
S415 | Phosphorylation | score0 | HPRD | 19413330, 18691976, 18491316, ... | ||
S470 | Phosphorylation | score0 | HPRD | 18669648 | ||
S530 | Phosphorylation | score0 | HPRD | 18669648 | ||
S534 | Phosphorylation | score0 | HPRD | 20068231 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
A2 | T2 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S98 | F98 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
K103 | N103 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S326 | F326 | Biomuta | DOID:2394 / ovarian cancer [ cosmic ] | |
S327 | C327 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] |