Protein Information

Cytoscape View


UniProt AC / UniProt ID O00757 / F16P2_HUMAN
Protein Name Fructose-1,6-bisphosphatase isozyme 2
Gene Name Name: FBP2
Organism Homo sapiens (Human)

PRO ID PR:O00757
DAG View
PRO Name fructose-1,6-bisphosphatase isozyme 2 (human)
Definition A fructose-1,6-bisphosphatase isozyme 2 that is encoded in the genome of human.
Short Label hFBP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00757 (FBP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y17 Phosphorylation PhosphoSitePlus
T28 Phosphorylation PhosphoSitePlus
T40 Phosphorylation PhosphoSitePlus
Y210 Phosphorylation PhosphoSitePlus
Y216 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
Y219 Phosphorylation PhosphoSitePlus
K231 Acetylation PhosphoSitePlus
Y245 Phosphorylation PhosphoSitePlus
T256 Phosphorylation IEDB 35494241
Y259 Phosphorylation PhosphoSitePlus
Y265 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T28 S28 Biomuta DOID:1319 / brain cancer [ cosmic ]
T40 M40 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic, icgc ]
Y216 C216 Biomuta DOID:1324 / lung cancer [ cosmic ]
K231 N231 Biomuta DOID:9256 / colorectal cancer [ cosmic ]