iPTMnet Report for O00625 (PIR)
Protein Information
UniProt AC / UniProt ID | O00625 / PIR_HUMAN |
Protein Name | Pirin |
Gene Name | Name: PIR |
Organism | Homo sapiens (Human) |
PRO ID | PR:O00625 |
PRO Name | pirin (human) |
Definition | A pirin that is encoded in the genome of human. |
Short Label | hPIR |
Category | organism-gene |
O00625 (PIR) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T8 | O-Glycosylation | score1 | PhosphoSitePlus | |||
T8 | Phosphorylation | score0 | HPRD | 20068231 | ||
S17 | Phosphorylation | score1 | PhosphoSitePlus | |||
K34 | Ubiquitination | score1 | PhosphoSitePlus | |||
R97 | Methylation | score1 | PhosphoSitePlus | |||
C106 | Methylation | score1 | IEDB | 31844290 | ||
Y131 | Phosphorylation | score1 | PhosphoSitePlus | |||
K135 | Sumoylation | score1 | PhosphoSitePlus | |||
S161 | Phosphorylation | score1 | PhosphoSitePlus | |||
K175 | Acetylation | score1 | PhosphoSitePlus | |||
K181 | Ubiquitination | score1 | PhosphoSitePlus | |||
S183 | Phosphorylation | score1 | PhosphoSitePlus | |||
K234 | Acetylation | score1 | PhosphoSitePlus | |||
K275 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S17 | L17 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
K135 | E135 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
K234 | N234 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
K275 | T275 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] |