Protein Information

Cytoscape View


UniProt AC / UniProt ID O00445 / SYT5_HUMAN
Protein Name Synaptotagmin-5
Gene Name Name: SYT5
Organism Homo sapiens (Human)

PRO ID PR:O00445
DAG View
PRO Name synaptotagmin-5 (human)
Definition A synaptotagmin-5 that is encoded in the genome of human.
Short Label hSYT5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00445 (SYT5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T15 Phosphorylation PhosphoSitePlus
S19 Phosphorylation PhosphoSitePlus
S20 Phosphorylation PhosphoSitePlus
T59 Phosphorylation PhosphoSitePlus
Y81 Phosphorylation PhosphoSitePlus
Y196 Phosphorylation PhosphoSitePlus
S202 Phosphorylation PhosphoSitePlus
K268 Acetylation PhosphoSitePlus
Y278 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T15 R15 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T59 R59 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y196 H196 Biomuta [ cosmic ]
K268 T268 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y278 * Biomuta DOID:1324 / lung cancer [ cosmic ]