iPTMnet Report for O00217 (NDUFS8)
Protein Information
| UniProt AC / UniProt ID | O00217 / NDUS8_HUMAN |
| Protein Name | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial precursor |
| Gene Name | Name: NDUFS8 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O00217 |
| PRO Name | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (human) |
| Definition | An NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial that is encoded in the genome of human. |
| Short Label | hNDUFS8 |
| Category | organism-gene |
DAG ViewO00217 (NDUFS8) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| Y38 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K49 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T52 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S73 | Phosphorylation | score0 | HPRD | 20068231 | ||
| Y74 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K88 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R96 | Methylation | score1 | PhosphoSitePlus | |||
| R133 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S73 | G73 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| R133 | G133 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| R133 | K133 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |
