iPTMnet Report for O00214 (LGALS8)
Protein Information
UniProt AC / UniProt ID | O00214 / LEG8_HUMAN |
Protein Name | Galectin-8 |
Gene Name | Name: LGALS8 |
Organism | Homo sapiens (Human) |
PRO ID | PR:O00214 |
PRO Name | galectin-8 (human) |
Definition | A galectin-8 that is encoded in the genome of human. |
Short Label | hLGALS8 |
Category | organism-gene |
O00214 (LGALS8) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S54 | Phosphorylation | score1 | PhosphoSitePlus | |||
S55 | Phosphorylation | score1 | PhosphoSitePlus | |||
K57 | Ubiquitination | score1 | PhosphoSitePlus | |||
K85 | Ubiquitination | score1 | PhosphoSitePlus | |||
K98 | Ubiquitination | score1 | PhosphoSitePlus | |||
K134 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y141 | Phosphorylation | score1 | PhosphoSitePlus | |||
K177 | Ubiquitination | score1 | PhosphoSitePlus | |||
T193 | Phosphorylation | score1 | PhosphoSitePlus | |||
T200 | Phosphorylation | score1 | PhosphoSitePlus | |||
K204 | Ubiquitination | score1 | PhosphoSitePlus | |||
K212 | Ubiquitination | score1 | PhosphoSitePlus | |||
K222 | Ubiquitination | score1 | PhosphoSitePlus | |||
K224 | Ubiquitination | score1 | PhosphoSitePlus | |||
K237 | Ubiquitination | score1 | PhosphoSitePlus | |||
K291 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T180 | Phosphorylation | score1 | PhosphoSitePlus | |||
K193 | Methylation | score1 | PhosphoSitePlus | |||
K193 | Ubiquitination | score1 | PhosphoSitePlus | |||
K204 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S55 | G55 | Biomuta | DOID:2394 / ovarian cancer [ cosmic ] | |
K85 | E85 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
T180 | M180 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K193 | I193 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
K224 | Q224 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |