iPTMnet Report for O00193 (SMAP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O00193 / SMAP_HUMAN
Protein Name Small acidic protein
Gene Name Name: SMAP
Synonyms:C11orf58;
Organism Homo sapiens (Human)

PRO ID PR:O00193
DAG View
PRO Name small acidic protein (human)
Definition A small acidic protein that is encoded in the genome of human.
Short Label hSMAP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00193 (SMAP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
S7 Phosphorylation PhosphoSitePlus
K13 Acetylation PhosphoSitePlus
R14 Methylation PhosphoSitePlus
S15 O-Glycosylation GlyGen 31373491
S15 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18691976, 17081983, ...18220336, 19562805, 20058876, 19664995, 18452278, 19651622, 18669648, 20166139, 19690332, 20068231
S17 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163, ...17081983, 18691976, 15302935, 16094384, 20058876, 19664995, 18452278, 19651622, 18669648, 19415658, 17693683, 20166139, 18707149, 19690332, 20068231
S24 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18691976, 17081983, 18220336, ...20058876, 19664995
S25 O-Glycosylation GlyGen 31373491
S25 Phosphorylation HPRD   PhosphoSitePlus 19413330, 20058876, 19664995
K38 Acetylation PhosphoSitePlus
K49 Acetylation PhosphoSitePlus
K50 Acetylation PhosphoSitePlus
R55 Methylation PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
S63 Phosphorylation PhosphoSitePlus   UniProt 23186163
K74 Acetylation PhosphoSitePlus
K75 Ubiquitination PhosphoSitePlus
S82 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y84 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 15592455
S87 Phosphorylation PhosphoSitePlus   UniProt 23186163
K91 Acetylation PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
S93 Phosphorylation PhosphoSitePlus
S105 Phosphorylation HPRD 17081983
S127 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 17081983, 20068231
S132 Phosphorylation HPRD   PhosphoSitePlus 17081983
S136 Phosphorylation HPRD   PhosphoSitePlus 17081983
S138 Phosphorylation HPRD   PhosphoSitePlus 17081983
S140 Phosphorylation HPRD   PhosphoSitePlus 17081983
S142 Phosphorylation HPRD   PhosphoSitePlus 17081983
S147 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 17081983, ...18767875, 18452278, 19651622, 20068231
Y173 Phosphorylation PhosphoSitePlus
K174 Acetylation PhosphoSitePlus   UniProt 19608861
K174 Ubiquitination PhosphoSitePlus
K179 Acetylation PhosphoSitePlus   UniProt 19608861
K179 Methylation PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S15 L15 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
R55 H55 Biomuta DOID:4159 / skin cancer [ cosmic ]
R55 C55 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
K75 R75 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K75 N75 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S82 C82 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]
K91 T91 Biomuta DOID:3571 / liver cancer [ cosmic ]
S142 P142 Biomuta DOID:9256 / colorectal cancer [ cosmic ]