iPTMnet Report for O00165 (HAX1)
Protein Information
UniProt AC / UniProt ID | O00165 / HAX1_HUMAN |
Protein Name | HCLS1-associated protein X-1 |
Gene Name | Name: HAX1 Synonyms:HS1BP1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O00165 |
PRO Name | HCLS1-associated protein X-1 (human) |
Definition | An HCLS1-associated protein X-1 that is encoded in the genome of human. |
Short Label | hHAX1 |
Category | organism-gene |
O00165 (HAX1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Acetylation | score1 | UniProt | 25944712 | ||
S53 | Phosphorylation | score1 | PhosphoSitePlus | |||
S66 | Phosphorylation | score1 | PhosphoSitePlus | |||
S68 | Phosphorylation | score1 | PhosphoSitePlus | |||
T124 | Phosphorylation | score1 | PhosphoSitePlus | |||
K131 | Ubiquitination | score1 | PhosphoSitePlus | |||
S135 | O-Glycosylation | score1 | GlyGen | 22121020, 35254053 | ||
R139 | Methylation | score1 | PhosphoSitePlus | |||
S153 | Phosphorylation | score1 | PhosphoSitePlus | |||
S162 | Phosphorylation | score1 | PhosphoSitePlus | |||
T181 | Phosphorylation | score1 | PhosphoSitePlus | |||
S189 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S192 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K205 | Ubiquitination | score1 | PhosphoSitePlus | |||
K209 | Ubiquitination | score1 | PhosphoSitePlus | |||
S210 | Phosphorylation | score1 | PhosphoSitePlus | |||
S212 | Phosphorylation | score1 | PhosphoSitePlus | |||
T214 | Phosphorylation | score1 | PhosphoSitePlus | |||
K215 | Ubiquitination | score1 | PhosphoSitePlus | |||
K218 | Ubiquitination | score1 | PhosphoSitePlus | |||
S255 | Phosphorylation | score1 | PhosphoSitePlus | |||
S266 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S2 | N2 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S66 | G66 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S153 | F153 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ] | |
S162 | F162 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
S189 | F189 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] | |
S212 | P212 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
S212 | F212 | Biomuta | DOID:1319 / brain cancer [ icgc ] | |
S266 | F266 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] |