iPTMnet Report for A6NMX2 (EIF4E1B)
Protein Information
| UniProt AC / UniProt ID | A6NMX2 / I4E1B_HUMAN |
| Protein Name | Eukaryotic translation initiation factor 4E type 1B |
| Gene Name | Name: EIF4E1B |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:A6NMX2 |
| PRO Name | eukaryotic translation initiation factor 4E type 1B (human) |
| Definition | A eukaryotic translation initiation factor 4E type 1B that is encoded in the genome of human. |
| Short Label | hEIF4E1B |
| Category | organism-gene |
DAG ViewA6NMX2 (EIF4E1B) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S44 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T51 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T183 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T192 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T51 | M51 | Biomuta | [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:1115 / sarcoma [ icgc ] | |
| T51 | P51 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T183 | I183 | Biomuta | [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] DOID:1115 / sarcoma [ icgc ] | |
| T183 | N183 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |
