Protein Information

Cytoscape View


UniProt AC / UniProt ID A6NM62 / LRC53_HUMAN
Protein Name Leucine-rich repeat-containing protein 53
Gene Name Name: LRRC53
Organism Homo sapiens (Human)

PRO ID PR:A6NM62
DAG View
PRO Name leucine-rich repeat-containing protein 53 (human)
Definition A protein that is a translation product of the LRRC53 gene in human.
Short Label hLRRC53
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


A6NM62 (LRRC53) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S95 Phosphorylation PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus
S108 Phosphorylation PhosphoSitePlus
T130 Phosphorylation PhosphoSitePlus
S131 Phosphorylation PhosphoSitePlus
T134 Phosphorylation PhosphoSitePlus
K1000 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T130 A130 Biomuta DOID:1324 / lung cancer [ cosmic ]
T134 I134 Biomuta DOID:2531 / hematologic cancer [ cosmic ]