iPTMnet Report for A6NKT7 (RGPD3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID A6NKT7 / RGPD3_HUMAN
Protein Name RanBP2-like and GRIP domain-containing protein 3
Gene Name Name: RGPD3
Synonyms:RGP3;
Organism Homo sapiens (Human)

PRO ID PR:A6NKT7
DAG View
PRO Name RanBP2-like and GRIP domain-containing protein 3 (human)
Definition A RanBP2-like and GRIP domain-containing protein 3 that is encoded in the genome of human.
Short Label hRGPD3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


A6NKT7 (RGPD3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K34 Ubiquitination PhosphoSitePlus
Y36 Phosphorylation PhosphoSitePlus
K40 Ubiquitination PhosphoSitePlus
Y42 Phosphorylation PhosphoSitePlus
Y70 Phosphorylation PhosphoSitePlus
S86 Phosphorylation PhosphoSitePlus
T92 Phosphorylation PhosphoSitePlus
K94 Ubiquitination PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus
K123 Acetylation PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
S128 Phosphorylation PhosphoSitePlus
K133 Ubiquitination PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
S199 Phosphorylation PhosphoSitePlus
S200 Phosphorylation PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus
C320 Methylation IEDB 31844290
K336 Ubiquitination PhosphoSitePlus
S353 Phosphorylation PhosphoSitePlus
S355 Phosphorylation PhosphoSitePlus
S363 Phosphorylation PhosphoSitePlus
K366 Ubiquitination PhosphoSitePlus
S381 Phosphorylation PhosphoSitePlus
Y387 Phosphorylation PhosphoSitePlus
S392 Phosphorylation PhosphoSitePlus
S393 Phosphorylation PhosphoSitePlus
S395 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
C537 Methylation IEDB 31844290
Y599 Phosphorylation PhosphoSitePlus
Y606 Phosphorylation PhosphoSitePlus
K608 Ubiquitination PhosphoSitePlus
K609 Ubiquitination PhosphoSitePlus
K615 Ubiquitination PhosphoSitePlus
K620 Ubiquitination PhosphoSitePlus
S731 Phosphorylation PhosphoSitePlus
K734 Ubiquitination PhosphoSitePlus
Y764 Phosphorylation PhosphoSitePlus
S768 Phosphorylation PhosphoSitePlus
S779 Phosphorylation PhosphoSitePlus
T780 Phosphorylation PhosphoSitePlus
S782 Phosphorylation PhosphoSitePlus
K785 Ubiquitination PhosphoSitePlus
Y786 Phosphorylation PhosphoSitePlus
S787 Phosphorylation PhosphoSitePlus
S789 Phosphorylation PhosphoSitePlus
S791 Phosphorylation PhosphoSitePlus
K792 Ubiquitination PhosphoSitePlus
S793 Phosphorylation PhosphoSitePlus
Y794 Phosphorylation PhosphoSitePlus
Y796 Phosphorylation PhosphoSitePlus
S797 Phosphorylation PhosphoSitePlus
K799 Ubiquitination PhosphoSitePlus
T800 Phosphorylation PhosphoSitePlus
S810 Phosphorylation PhosphoSitePlus
R891 Methylation PhosphoSitePlus
T897 Phosphorylation PhosphoSitePlus
K900 Ubiquitination PhosphoSitePlus
K911 Ubiquitination PhosphoSitePlus
S915 Phosphorylation PhosphoSitePlus
S919 O-Glycosylation GlyGen   PhosphoSitePlus 33214551, 31492838, 34019948, ...30620550
S919 Phosphorylation PhosphoSitePlus
K924 Ubiquitination PhosphoSitePlus
S928 Phosphorylation PhosphoSitePlus
K935 Ubiquitination PhosphoSitePlus
T971 Phosphorylation PhosphoSitePlus
S978 Phosphorylation PhosphoSitePlus
T979 Phosphorylation PhosphoSitePlus
S980 Phosphorylation PhosphoSitePlus
K988 Ubiquitination PhosphoSitePlus
K994 Methylation PhosphoSitePlus
K994 Ubiquitination PhosphoSitePlus
S997 Phosphorylation PhosphoSitePlus
K1002 Acetylation PhosphoSitePlus
K1002 Ubiquitination PhosphoSitePlus
S1006 Phosphorylation PhosphoSitePlus
Y1008 Phosphorylation PhosphoSitePlus
T1017 Phosphorylation PhosphoSitePlus
S1018 Phosphorylation PhosphoSitePlus
Y1028 Phosphorylation PhosphoSitePlus
T1030 Phosphorylation PhosphoSitePlus
S1033 Phosphorylation PhosphoSitePlus
K1047 Ubiquitination PhosphoSitePlus
K1058 Ubiquitination PhosphoSitePlus
K1066 Ubiquitination PhosphoSitePlus
K1078 Ubiquitination PhosphoSitePlus
K1086 Ubiquitination PhosphoSitePlus
C1109 Methylation IEDB 31844290
K1121 Ubiquitination PhosphoSitePlus
R1128 Methylation PhosphoSitePlus
K1152 Ubiquitination PhosphoSitePlus
T1153 Phosphorylation PhosphoSitePlus
K1161 Ubiquitination PhosphoSitePlus
K1163 Ubiquitination PhosphoSitePlus
T1178 Phosphorylation PhosphoSitePlus
K1181 Ubiquitination PhosphoSitePlus
T1185 Phosphorylation PhosphoSitePlus
K1190 Ubiquitination PhosphoSitePlus
K1199 Ubiquitination PhosphoSitePlus
S1200 Phosphorylation PhosphoSitePlus
K1203 Ubiquitination PhosphoSitePlus
K1206 Sumoylation PhosphoSitePlus
K1206 Ubiquitination PhosphoSitePlus
Y1252 Phosphorylation PhosphoSitePlus
S1262 Phosphorylation PhosphoSitePlus
S1264 Phosphorylation PhosphoSitePlus
S1265 Phosphorylation PhosphoSitePlus
S1266 Phosphorylation PhosphoSitePlus
S1267 Phosphorylation PhosphoSitePlus
S1271 Phosphorylation PhosphoSitePlus
S1275 Phosphorylation PhosphoSitePlus
S1276 Phosphorylation P06493 (CDK1) PhosphoSitePlus 18234856
S1301 Phosphorylation PhosphoSitePlus
S1303 Phosphorylation PhosphoSitePlus
K1304 Ubiquitination PhosphoSitePlus
S1305 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
K1308 Ubiquitination PhosphoSitePlus
S1312 Phosphorylation PhosphoSitePlus
T1314 Phosphorylation PhosphoSitePlus
S1315 Phosphorylation PhosphoSitePlus
T1318 Phosphorylation PhosphoSitePlus
S1322 Phosphorylation PhosphoSitePlus
T1325 Phosphorylation PhosphoSitePlus
K1369 Ubiquitination PhosphoSitePlus
K1375 Ubiquitination PhosphoSitePlus
K1383 Ubiquitination PhosphoSitePlus
K1404 Ubiquitination PhosphoSitePlus
T1412 Phosphorylation PhosphoSitePlus
S1416 Phosphorylation PhosphoSitePlus
K1421 Ubiquitination PhosphoSitePlus
T1423 Phosphorylation PhosphoSitePlus
K1440 Acetylation PhosphoSitePlus
K1449 Sumoylation PhosphoSitePlus
K1449 Ubiquitination PhosphoSitePlus
S1456 Phosphorylation PhosphoSitePlus
K1459 Ubiquitination PhosphoSitePlus
K1465 Ubiquitination PhosphoSitePlus
T1466 Phosphorylation PhosphoSitePlus
K1470 Ubiquitination PhosphoSitePlus
S1472 Phosphorylation PhosphoSitePlus
T1475 Phosphorylation PhosphoSitePlus
S1479 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S1481 Phosphorylation PhosphoSitePlus
S1482 Phosphorylation PhosphoSitePlus
T1483 Phosphorylation PhosphoSitePlus
S1487 Phosphorylation PhosphoSitePlus
K1491 Ubiquitination PhosphoSitePlus
T1500 Phosphorylation PhosphoSitePlus
T1501 Phosphorylation PhosphoSitePlus
T1525 Phosphorylation PhosphoSitePlus
S1526 Phosphorylation PhosphoSitePlus
T1528 Phosphorylation PhosphoSitePlus
T1529 Phosphorylation PhosphoSitePlus
T1530 Phosphorylation PhosphoSitePlus
S1535 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K1538 Sumoylation PhosphoSitePlus
K1538 Ubiquitination PhosphoSitePlus
S1543 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1545 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K1547 Ubiquitination PhosphoSitePlus
S1551 Phosphorylation PhosphoSitePlus
K1556 Sumoylation PhosphoSitePlus
S1564 Phosphorylation PhosphoSitePlus
S1568 Phosphorylation PhosphoSitePlus
S1573 Phosphorylation PhosphoSitePlus
K1579 Methylation PhosphoSitePlus
K1579 Sumoylation PhosphoSitePlus
S1583 Phosphorylation PhosphoSitePlus
T1585 Phosphorylation PhosphoSitePlus
S1591 Phosphorylation PhosphoSitePlus
S1593 Phosphorylation PhosphoSitePlus
K1596 Sumoylation PhosphoSitePlus
K1596 Ubiquitination PhosphoSitePlus
S1605 Phosphorylation PhosphoSitePlus
K1606 Ubiquitination PhosphoSitePlus
S1608 Phosphorylation PhosphoSitePlus
S1614 Phosphorylation PhosphoSitePlus
K1617 Sumoylation PhosphoSitePlus
K1619 Ubiquitination PhosphoSitePlus
S1622 Phosphorylation PhosphoSitePlus
Y1634 Phosphorylation PhosphoSitePlus
T1638 Phosphorylation PhosphoSitePlus
K1658 Ubiquitination PhosphoSitePlus
S1660 Phosphorylation PhosphoSitePlus
K1664 Ubiquitination PhosphoSitePlus
S1665 Phosphorylation PhosphoSitePlus
K1691 Ubiquitination PhosphoSitePlus
K1724 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y36 * Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K106 T106 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K106 E106 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K123 T123 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K123 N123 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S200 N200 Biomuta DOID:1612 / breast cancer [ cosmic ]
S205 L205 Biomuta [ cosmic ] DOID:363 / uterine cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:1115 / sarcoma [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S353 R353 Biomuta DOID:1324 / lung cancer [ cosmic ]
K734 N734 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y764 H764 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S768 Y768 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S779 F779 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ]
S779 Y779 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S782 F782 Biomuta DOID:4159 / skin cancer [ cosmic ]
K785 R785 Biomuta DOID:3565 / meningioma [ cosmic ] DOID:2531 / hematologic cancer [ cosmic, icgc ]
K785 Q785 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S787 * Biomuta DOID:3571 / liver cancer [ cosmic ]
S787 L787 Biomuta DOID:4159 / skin cancer [ cosmic ]
S791 N791 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S793 R793 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y796 C796 Biomuta DOID:1324 / lung cancer [ icgc ]
Y796 F796 Biomuta DOID:1324 / lung cancer [ cosmic ]
S797 Y797 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S810 Y810 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T897 S897 Biomuta DOID:1612 / breast cancer [ cosmic ]
S915 F915 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K924 E924 Biomuta DOID:4159 / skin cancer [ cosmic ]
S928 L928 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ]
K935 N935 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S978 L978 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T979 A979 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S997 L997 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1006 * Biomuta DOID:4159 / skin cancer [ cosmic ]
Y1008 C1008 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
T1017 N1017 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
K1058 N1058 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]
K1078 N1078 Biomuta DOID:4159 / skin cancer [ cosmic ]
K1163 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K1190 T1190 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic ]
S1200 T1200 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S1200 R1200 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1262 N1262 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S1275 R1275 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1303 C1303 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1303 Y1303 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K1304 M1304 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
K1304 R1304 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1312 R1312 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1322 F1322 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1416 G1416 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K1440 N1440 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K1440 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K1449 I1449 Biomuta DOID:4159 / skin cancer [ cosmic ]
K1449 N1449 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1456 W1456 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1472 Y1472 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1472 F1472 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic, icgc ]
T1475 R1475 Biomuta DOID:4159 / skin cancer [ cosmic ]
K1556 N1556 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S1660 R1660 Biomuta DOID:363 / uterine cancer [ cosmic ]
S1665 R1665 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]