iPTMnet Report for A6NE01 (FAM186A)
Protein Information
UniProt AC / UniProt ID | A6NE01 / F186A_HUMAN |
Protein Name | Protein FAM186A |
Gene Name | Name: FAM186A |
Organism | Homo sapiens (Human) |
PRO ID | PR:A6NE01 |
PRO Name | protein FAM186A (human) |
Definition | A protein FAM186A that is encoded in the genome of human. |
Short Label | hFAM186A |
Category | organism-gene |
A6NE01 (FAM186A) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
R79 | Methylation | score1 | PhosphoSitePlus | |||
R83 | Methylation | score1 | PhosphoSitePlus | |||
T115 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
S182 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
S262 | Phosphorylation | score1 | PhosphoSitePlus | |||
S263 | Phosphorylation | score1 | PhosphoSitePlus | |||
S273 | Phosphorylation | score1 | PhosphoSitePlus | |||
K280 | Ubiquitination | score1 | PhosphoSitePlus | |||
K549 | Acetylation | score1 | PhosphoSitePlus | |||
K551 | Acetylation | score1 | PhosphoSitePlus | |||
S613 | Phosphorylation | score1 | PhosphoSitePlus | |||
K632 | Acetylation | score1 | PhosphoSitePlus | |||
K648 | Acetylation | score1 | PhosphoSitePlus | |||
K715 | Ubiquitination | score1 | PhosphoSitePlus | |||
S767 | Phosphorylation | score1 | PhosphoSitePlus | |||
S770 | Phosphorylation | score1 | PhosphoSitePlus | |||
S773 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y854 | Phosphorylation | score1 | PhosphoSitePlus | |||
K874 | Acetylation | score1 | PhosphoSitePlus | |||
T1005 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1008 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1010 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1024 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1698 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1701 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1704 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1730 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1960 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1961 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1964 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1965 | Acetylation | score1 | PhosphoSitePlus | |||
S1972 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1977 | Acetylation | score1 | PhosphoSitePlus | |||
T2039 | Phosphorylation | score1 | PhosphoSitePlus | |||
T2052 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y2185 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2195 | Phosphorylation | score1 | PhosphoSitePlus | |||
K2225 | Acetylation | score1 | PhosphoSitePlus | |||
K2234 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R79 | W79 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
R79 | Q79 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
R83 | C83 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
S182 | Y182 | Biomuta | DOID:10534 / stomach cancer [ icgc ] | |
S182 | F182 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S262 | * | Biomuta | DOID:4362 / cervical cancer [ cosmic ] | |
S273 | N273 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S613 | Y613 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K874 | Q874 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
T1008 | A1008 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
S1010 | Y1010 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
Y1024 | H1024 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
S1701 | L1701 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] | |
S1960 | Y1960 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] |